Medications


Aspirin; Caffeine; Orphenadrine oral tablets

What is this medicine?

Aspirin; caffeine; orphenadrine combination helps to relieve pain and stiffness in muscles and can treat muscle spasms.

How should I use this medicine?

Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.

Talk to your pediatrician about the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • bleeding

  • breathing problems

  • severe bruising

  • unusually weak or tired

Side effects that usually do not require medical attention (Report these to your doctor or health care professional if they continue or are bothersome.):

  • blurred vision

  • constipation

  • difficulty urinating

  • dizziness

  • dry mouth

  • fast heart rate

  • headache

  • nausea

  • weakness

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • cidofovir

  • ketorolac

  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate

  • narcotic medicines for cough

  • probenecid

This medicine may also interact with the following medications:

  • alcohol

  • antihistamines for allergy, cough, and cold

  • certain medicines for anxiety or sleep

  • certain medicines for depression like amitriptyline, fluoxetine, sertraline

  • certain medicines for seizures like phenobarbital, primidone

  • cyclobenzaprine

  • general anesthetics like halothane, isoflurane, methoxyflurane, propofol

  • local anesthetics like lidocaine, pramoxine, tetracaine

  • medicines that relax muscles for surgery

  • medicines that treat or prevent blood clots like enoxaparin, heparin, ticlopidine, warfarin

  • narcotic medicines for pain

  • NSAIDs, medicines for pain and inflammation, like ibuprofen and naproxen

  • other aspirin and aspirin-like medicines

  • phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F).

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • bleeding disorders

  • glaucoma

  • kidney disease

  • myasthenia gravis

  • peptic ulcer disease

  • prostate disease

  • stomach problems

  • an unusual or allergic reaction to aspirin, caffeine, orphenadrine, other medicines, foods, lactose, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Tell your doctor or health care professional if your symptoms do not start to get better or if they get worse.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

If you are taking another medicine that also causes drowsiness, you may have more side effects. Give your health care provider a list of all medicines you use. Your doctor will tell you how much medicine to take. Do not take more medicine than directed. Call emergency for help if you have problems breathing or unusual sleepiness.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.

Do not take aspirin or aspirin-like medicines with this medicine. Too much aspirin can be dangerous. Always read the labels of other medicines carefully.


NOTE:This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Copyright© 2019 Elsevier
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